A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...

Medicines come from chemical reactions, and better chemical reactions lead to better medicines. Yet, the most popular reaction used in drug discovery, called the amide coupling, makes an inherently ...

Even though amide bonds are everywhere—they hold proteins together and are essential components in many drugs—forging this molecular motif in a reaction flask can be challenging. For example, making ...

Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. Scientists have now introduced a new type of reaction for making amide ...

It’s dinnertime, and the only food in your house is a can of beans and a box of spaghetti. What can you make? A new mapping method that combines known reactants in unfamiliar ways can help organic ...

Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...