Once people realized that opioid drugs could cause addiction and deadly overdoses, they tried to use newer forms of opioids to treat the addiction to its parent. Morphine, about 10 times the strength ...

The Annals of Pharmacotherapy. 2006;40(7):1327-1335. The classification of opioid analgesics may be based on 3 different schemes: (1) analog class (phenanthrene, phenylpiperidine, diphenylheptane), (2 ...

For the better part of a decade, scientists have been trying to engineer microbes to produce morphine and other opioid painkillers directly from glucose. Some say such engineered microbes could reduce ...

LONDON (Reuters) - Scientists have identified a key gene used by poppies to make morphine, paving the way for better methods of producing the medically important drug, potentially without the need for ...

The objectives of the experiments presented in this manuscript were as follows: to determine whether chronic codeine administration induces hyperalgesia to the same degree as chronic morphine ...

Scientists have discovered metabolic enzymes in the opium poppy that play "widespread roles" in enabling the plant to make painkilling morphine and codeine, and other important compounds. University ...

This isn't an isolated concern. The American Academy of Pediatrics, the American College of Chest Physicians, the Canadian Ministry of Health, European Medicines Agency, and the U.S. Food and Drug ...

Frequent and large does of codeine may increase sensitivity to pain and fail to offer the same relief as morphine, according to a study presented at the 2013 International Headache Congress in the US.

Using large and frequent doses of the pain-killer codeine may actually produce heightened sensitivity to pain, without the same level of relief offered by morphine, according to new research. Using ...