A team at UNC-Chapel Hill has developed a new process for synthesizing amides in a 100% atom-economical, sustainable fashion using earth-abundant cobalt. The group has developed a method for producing ...

image: A series of amines, including synthetic challenging primary amines were synthesized with highly tolerance of other reducible functional groups. Mechanistic studies from control experiments and ...

A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...

A new reaction cuts nitrogen atoms out of secondary amines with surgical precision. The transformation offers a route to strained structures, such as cyclobutanes (example shown), that can be ...